Read e-book online Advances in veterinary science and comparative medicine. PDF

By James L Bittle; Frederick A Murphy

ISBN-10: 012039233X

ISBN-13: 9780120392339

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Extra info for Advances in veterinary science and comparative medicine. Vol. 33, Vaccine biotechnology

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A polyvalent pneumococcal vaccine prepared from soluble purified capsular polysaccharides of the 23 most predominant S. pneumoniae serotypes has proven effective in adults. , 1982). However, vaccination of infants has not proven beneficial, because they develop no higher antibody titers to the bacteria t h a n do unvaccinated infants (Ginsburg, 1986). IV. Vaccines for Gram-Negative Bacteria A. Entobacteria 1. Escherichia coli 2. Salmonella spp. 3. Yersinia pestis Ε. Brucella 1. Β. abortus 2. B.

Recombinant DNA technology, discussed in the chapter by Collett has introduced the potential to construct E. coli vaccine strains t h a t would afford considerably better protection than those currently available. 2. Salmonella spp. Salmonella species are a major cause of invasive enteric infections in humans and domestic animals, with domestic poultry constituting the largest reservoir of Salmonella organisms in nature. Normally, infection occurs through the oral route. Salmonella is a facultative intracellular pathogen; therefore, cell-mediated immunity is more important than humoral immunity in resistance to the disease, salmonellosis (Fields et ah, 1986a,b; Dougan et ah, 1987; Woolcock, 1973).

Most Hemophilus species require two factors, hemin (X) and nicotinamide adenine dinucleotide (V), for growth. Antigens associated with protection and virulence have been described fori/, paragallinarum (Yamamoto, 1984), the etiologic agent of infectious coryza in chickens. , 1963); immunity is serotype-specific. Adjuvanted vaccines containing multiple bacterial serotypes are prepared from chicken embryos or formalinized bacterial broth cultures and are effective vaccines in preventing infectious coryza in chickens.

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Advances in veterinary science and comparative medicine. Vol. 33, Vaccine biotechnology by James L Bittle; Frederick A Murphy

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